We show that VEGF lead... With UC2 (You-See-Too) we present an inexpensive 3D-printed microscopy toolbox. Contrary to the assumption that ACE levels are stable, circulating ACE has been shown to be altered in obesity and weight loss. CAT12 Toolbox (for SPM12) Download the newest version from that Folder.. unpack the zip-file; remove the old cat12 folder; copy or link the cat12 folder to the spm12/toolbox directory The toolboxes are named according to the SPM version. Was aber sind Organ-on-a-Chip-Systeme und wo liegt ihre Anwendung? Electronic address: pergolacarlo@googlemail.com. Attractive, creative projects and internships at any time. Monika Keilich Friedrich Schiller University Jena Leutragraben 1 07743 Jena. University of Jena Teaching Research Team Faculty Back Team Microeconomics Team Team Information about our team. Upper whisker shows the 90th, the lower whisker the 10th percentile. ); nderim_kryeziu@hotmail.com (N.K. In this study, we analyzed whether influenza A virus (IAV) and/or Staphylococcus aureus (S. aureus) infections affect SP-A express... AMP-activated protein kinase (AMPK) is activated by vascular endothelial growth factor (VEGF) in endothelial cells and it is significantly involved in VEGF-induced angiogenesis. Central institutions and faculties of Jena University. Besides viruses, bacterial co-infections dramatically exacerbate infection. alexander.mosig@med.uni-jena.de. Here, we describe highly specific nanoparticles, based on near infrared fluorescent polymethine dye-derived targeting moieties coupled to biodegradable polymers. 30 Sep 2020. B: Whisker box plots of log2 transformed microarray raw data. Julia Dinger. Tumour-associated macrophages mainly comprise immunosuppressive M2 phenotypes that promote tumour progression besides anti-tumoural M1 subsets. Long-chain metabolites of vitamin E: A new class of regulatory metabolites modulating atherogenic processes? human liver sinusoid. We will see you in Jena in the winter semester 2020/21—partly on site, partly online 10 July 2010 10 July 2010 Educational operations of the winter semester 2020/21 at the Friedrich Schiller University will start on 2 November 2020 and will be conducted—at least partially—on site. Please use the string “Application for PD position – SURNAME NAME” in the email subject and use the PDF format for all your files. The current in vitro gut models that... Alterations of the microbial composition in the gut and the concomitant dysregulation of the mucosal immune response are associated with the pathogenesis of opportunistic infections, chronic inflammation, and inflammatory bowel disease. The City of Jena. Molecular Hemostaseology, Friedrich‐Schiller‐University of Jena, Jena, Germany. Friedrich Schiller University, Institute of Microbiology. Learn more. In general, surfactant protein-A (SP-A) represents a first line of immune defense. Since 2015 Head of Research Group INSPIRE – In Vitro Sepsis Research, Center for Sepsis Control and Care . Alexander MOSIG, Research Group Leader INSPIRE of Universitätsklinikum Jena, Jena | Read 88 publications | Contact Alexander MOSIG We sought to examine effects of a high‐saturated‐fat (HF) diet on ACE within the NUtriGenomic A... Abstract Near infrared spectroscopy (NIRS) is a rapid and non-destructive method for compositional analysis of biological material. Center for Sepsis Control and Care (CSCC), French Institute of Health and Medical Research, Competence Cluster for Nutrition and Cardiovascular Health (nutriCARD), Center for Infectious Disease and Infection Control & Deparment of Anesthesiology and Intensive Care Medicine, Anesthesiology and Intensive Care Medicine, Rapid Target Binding and Cargo Release of Activatable Liposomes Bearing HER2 and FAP Single-Chain Antibody Fragments Reveal Potentials for Image-Guided Delivery to Tumors, SARS-CoV-2 causes severe alveolar inflammation and barrier dysfunction, Staphylococcus aureus Lung Infection Results in Down-Regulation of Surfactant Protein-A Mainly Caused by Pro-Inflammatory Macrophages, VEGF Triggers Transient Induction of Autophagy in Endothelial Cells via AMPKα1, UC2 - A Versatile and Customizable low-cost 3D-printed Optical Open-Standard for microscopic imaging, Co-infection with Staphylococcus aureus after primary influenza virus infection leads to damage of the endothelium in a human alveolus-on-a-chip model, The PPARγ antagonist 2-chloro-5-nitro-N-phenylbenzamide (GW9662) triggers PLIN2 expression via PPARδ and induces lipogenesis and triglyceride accumulation in human THP-1 macrophages, The vitamin E derivative α-amplexichromanol as anti-inflammatory lead inspired from traditional African medicine, Keeping Candida commensal – How lactobacilli antagonize pathogenicity of Candida albicans in an in vitro gut model, A three-dimensional immunocompetent intestine-on-chip model as in vitro platform for functional and microbial interaction studies, CAAP48, a New Sepsis Biomarker, Induces Hepatic Dysfunction in an in vitro Liver-on-Chip Model, UC2 – A 3D-printed General-Purpose Optical Toolbox for Microscopic Imaging, Candida albicans β-Glucan Differentiates Human Monocytes Into a Specific Subset of Macrophages, Endogenous metabolites of vitamin E limit inflammation by targeting 5-lipoxygenase, Raman spectroscopic investigation of the human liver stem cell line HepaRG, Microphysiological systems meet hiPSC technology – New tools for disease modeling of liver infections in basic research and drug development, Corrigendum: Monocyte-induced recovery of inflammation-associated hepatocellular dysfunction in a biochip-based human liver model, Functional analyses of RUNX3 and CaMKIINα in ovarian cancer cell lines reveal tumor-suppressive functions for CaMKIINα and dichotomous roles for RUNX3 transcript variants, Short-term treatment with taurolidine is associated with liver injury, Preservation of Cell Structure, Metabolism, and Biotransformation Activity of Liver-On-Chip Organ Models by Hypothermic Storage, Thermo-responsive cell culture carrier: Effects on macrophage functionality and detachment efficiency, Tribbles 2 mediates cisplatin sensitivity and DNA damage response in epithelial ovarian cancer, Evaluation of HepaRG cells for the assessment of indirect drug-induced hepatotoxicity using INH as a model substance, Organs-on-a-Chip: Neue Perspektiven in der Medikamentenentwicklung und Personalisierten Medizin, Selective upregulation of TNFα expression in classically-activated human monocyte-derived macrophages (M1) through pharmacological interference with VATPase, Modulation of actin dynamics as potential macrophage subtype-targeting anti-tumour strategy, High‐Saturated‐Fat Diet Increases Circulating Angiotensin‐Converting Enzyme, Which Is Enhanced by the rs4343 Polymorphism Defining Persons at Risk of Nutrient‐Dependent Increases of Blood Pressure, Novel approach for the prediction of cell densities and viability in standardized translucent cell culture biochips with near infrared spectroscopy, Crossing the blood-brain barrier: Glutathione-conjugated poly(ethylene imine) for gene delivery, Organ-on-chip models: new opportunities for biomedical research, An integrative microfluidically supported in vitro model of an endothelial barrier combined with cortical spheroids simulates effects of neuroinflammation in neocortex development, Recruitment of CD16+ monocytes to endothelial cells in response to LPS treatment and concomitant TNF release is regulated by CX3CR1 and interfered by soluble fractalkine, Monocyte-induced recovery of inflammation-associated hepatocellular dysfunction in a biochip-based human liver model, A human macrophage – hepatocyte co-culture model for comparative studies of infection and replication of Francisella tularensis LVS strain and subspecies holarctica and mediasiatica, A new fluorescent dye for cell tracing and mitochondrial imaging in vitro and in vivo, High fat diet induced association of anti-inflammatory phospholipid and CRP levels in human adipose tissue in the NUGAT study, A Microfluidically Perfused Three Dimensional Human Liver Model, Comparison of the uptake of methacrylate-based nanoparticles in static and dynamic in vitro systems as well as in vivo, A biochip-based liver organoid model of human sepsis. The Abbe School of Photonics (ASP) provides education programs with multidisciplinary coverage of optical and photonics technology field topics, ranging from current scientific aspects to engineering, with product applications possible in major economic sectors such as information and communication technologies, medicine and health, manufacturing and energy consumption. Email: falk.eilenberger@uni-jena.de Phone: +49 3641 9 47990 The Junior Research Group "Optics in 2D-Materials" is dedicated to the understanding of light-matter-interaction in atomically thin layers of nanomaterials, to the tailoring of their optical response, and to … (2)Institute of Forensic Medicine, Jena University Hospital, 07747, Jena, Germany. Statin therapy has no effect of SREBP gene expression in monocytes. S., et al. Studies on Franci... Mitochondria contribute to redox and calcium balance, and apoptosis thus regulating cellular fate. Institut für Biochemie II Universitätsklinikum Jena Nonnenplan 2-4 07743 Jena Telefon: +49 3641 9 390 910 Telefax: +49 3641 9 396 402 alexander.mosig@med.uni-jena.de Hepatic α-TOH catabolism results in intermediate formation of long-chain metabolites (α-LCMs(5)) α-13'-hydroxy- and α-13'-carboxychromanol (α-13'-OH(6) and α-13'-COOH(7)). 3,149 Followers, 89 Following, 94 Posts - See Instagram photos and videos from UNISPORT Jena (@unisport_jena) There are no tuition fees at the Friedrich Schiller University Jena. Petra joined Jena University Hospital (JUH), Department of Anaesthesiology and Intensive Care Medicine, in November 2016 as senior academic clinical lecturer to connect her research interests and expertise with the infection research at JUH and its integrated research and treatment Centre for Sepsis Control and Care (CSCC). Cigarette smoke components have a proven negative influence on human health. Learn more. Identification of high fat diet induced inflammatory gene networks associated with suppression of anti-inflammatory phospholipids in human adipose tissue in the NUGAT (Nutrigenomics Analysis in Twins) study, Microfluidically supported biochip design for culture of endothelial cell layers with improved perfusion conditions, A microfluidically perfused three dimensional human liver model, Optimization of the transfection of human THP-1 macrophages by application of Nunc UpCell technology, Cell type-specific delivery of short interfering RNAs by dye-functionalised theranostic nanoparticles, High fat diet induced adipose tissue inflammation by suppression of anti-inflammatory phospholipids, Identification of gene-networks associated with specific lipid metabolites by Weighted Gene Co-Expression Network Analysis (WGCNA), Microfluidic devices for cell culture and handling in organ-on-a-chip applications, Long-chain metabolites of α-tocopherol occur in human serum and inhibit macrophage foam cell formation in vitro, SORBS2 and TLR3 induce premature senescence in primary human fibroblasts and keratinocytes, Analysis of glucose and fetal calf serum in aqueous solution for Multi Organ Tissue Flow (MOTiF) bioreactors using NIR Spectroscopy, Towards an understanding of the interaction between liver cells and antibiotics via Raman microspectroscopy, Antioxidative and Non-Antioxidative Effects of Tocopherol Metabolites on Atherogenesis, METHOD AND DEVICE FOR DETECTING THE MOTION AND ADSORPTION OF CELLS AND PARTICLES ON CELL, TISSUE, AND IMPLANT LAYERS IN THE SIMULATION OF FLOW CONDITIONS, Verfahren und Vorrichtung zur Erfassung der Bewegung und Anlagerung von Zellen und Partikeln an Zell-, Gewebe- und Implantatschichten bei der Simulation von Flussbedingungen, Gene Expression And Autologous Blood Transfusion - A New Advance Towards Blood Doping Detection?

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